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Advanced TreatmentWith Utmost Care

The Centre diagnoses and treats a wide variety of blood disorders and blood cancers, such as all kinds of anemia, marrow failure syndromes, coagulation disorders, acute and chronic leukemia, myelomas, lymphomas and myeloproliferative & lymphoproliferative disorders.

Its range of facilities and services include both Allogenic and Autologous transplant using bone marrow, peripheral blood stem cells and cord blood stem cells for various benign and malignant disorders.

State-of-the-art Infrastructure

The Centre is equipped with ultra-modern infrastructure and an internationally trained, widely experienced faculty. It is supported by state-of-the-art laboratory & transfusion services, along with a fully-equipped radiation oncology unit, with facilities for total body irradiation. The center is also an authorized stem cell collection center for DATRI Blood Stem Cell Donor’s Registery.

Centre’s key features include:

Treatment & Surgeries

Bone marrow transplantation is a procedure wherein stem cells from bone marrow that produce various blood cells like red blood cells, white blood cells and platelets are injected into a recipient. These stem cells are also referred to as hematopoietic stem cells. Nowadays, hematopoietic stem cells may also be obtained from peripheral blood after treatment with certain growth factors or from an umbilical cord. Thus, the term ‘Hematopoietic stem cell transplantation’ is now preferred to ‘Bone marrow transplantation’ to include these other sources of hematopoietic stem cells.

The bone marrow is a soft, spongy portion within a bone. It contains immature cells called stem cells that have a continuous ability to produce different types of blood cells i.e. red blood cells, white blood cells and platelets. These are then released into the blood stream. Bone marrow is of two types, red marrow and yellow marrow. In children, most of the marrow is red marrow and is rich in stem cells. In adults, however, a large portion of the bone marrow is converted into yellow marrow due to infiltration of fat cells. Red marrow in adults is usually restricted to a few bones like the hip bones, breast bone, ribs, shoulder blades, skull, backbone, and the ends of the arm and thigh bones.

Benign Hematological Disorders: Thalassemia, Sickle Cell Disease, Aplastic Anemia, Bleeding Disorders, Coagulation Disorders, etc.

Malignant Hematological Disorders: Acute and Chronic Leukemia (AML/ALL/CML/CLL), Hodgkins and Non-Hodgkins Lymphoma, Multiple Myeloma, Myelodysplasia (MDS), etc.

BMT actually means infusion of stem cells (collected either from bone marrow or peripheral blood or cord blood) into the recipient. The type of bone marrow that is used for the transplant distinguishes the different types of BMT.

  • Autologous BMT is done by using the patient’s own stem cells.
  • Allogeneic BMT involves using the stem cells of a donor. The donor may be a relative, usually a brother or sister, or an unrelated (anonymous) donor. The donor needs to be a Histocompatible Leukocyte antigen (HLA) match.

BMT Phases
There are three main phases to the BMT process:

Although the experience during these phases may be quite different for each patient, we shall describe a general overview here.

The journey of a patient through a transplant is divided into seven steps. Beginning with preparing for the journey, the steps tell you what to expect along the way.

1. Preparation: The preparation phase begins when the patient arrives at the treatment center and begins the process of medical evaluation, orientation, informed consent, and other preliminary activities.
a. Beginning Medical Evaluation
b. C onference for Treatment Plan
c. C entral Venous Catheter Evaluation and Insertion

2. Bone-Marrow/Stem Cells Harvest: Collection of the stem cells from either the bone marrow or peripheral blood by apheresis, from either the donor (in Allogenic transplant) or from the patient itself (in Autologus transplant).

3. Conditioning: The conditioning phase begins the actual transplant process. During this phase, high-dose chemotherapy, radiation therapy, or both are initiated. Chemotherapy and radiation therapy are given in doses that obliterate the marrow function and result in the greatest possibility of destroying the disease. Depending upon the chemotherapy agents and radiation therapy administration schedule, some conditioning therapy can be administered in the outpatient setting, thus potentially shortening the inpatient stay. The Preparation, Harvest and Conditioning together comprise the Pre-BMT Phase.

4. Transplant: The transplant phase is the infusion of donor bone marrow or stem cells. After the conditioning regimen is completed, the patient receives the infusion of bone marrow or stem cells. The duration beyond the transplant day is considered as the Post BMT phase.

5. Waiting for Engraftment: This phase includes close monitoring, supportive treatment, and management of complications while waiting for signs of engraftment (new cell growth).
a) Support, Protection and Close Monitoring
b) Watching and Managing Effects of Treatment

6. Engraftment and Early Recovery: Approximately 10 to 28 days after transplant, signs that the new bone marrow or stem cells are engrafting (growing and developing) can be expected. Close monitoring will continue along with supportive care. Preparation for the return of the patient to the referring physician or center will begin.

7. Long-Term Recovery:
The long-term recovery phase involves leaving the treatment center, dealing with any ongoing clinical issues, and re-establishing life patterns. Patients however need to follow up for any long term complications of BMT.

Our team ofBone Marrow Transplant

 

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Dr. Dharma Choudhary
Sr. Consultant & Director Bone Marrow Transplant

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Dr. Nimish Kulkarni
Bone Marrow Transplant

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Dr. Prathamesh Kulkarni
Bone Marrow Transplant​

Equipped with Latest Technology & Facilities

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Cancer Ward

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Cath Lab

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Centre for Liver & Digestive Diseases and Day Care

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Centre for Liver & Digestive Diseases and Day Care

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Corridor

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Critical Care Unit 1

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Critical Care Unit

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CT Scan

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Deluxe Hospital Room

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Doctors Lounge

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Executive Lounge

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Critical Care Unit ICU Wing (CCU 3)

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Spine OT

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Isolation Room

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MRI

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Nanavati Suite Room FIN New

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Nanavati Premium Room

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Nanavati Deluxe Bougainvillea

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Nanavati OT

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Nanavati ORTHO OT

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Nanavati Spine OT With MicroScope

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Nanavati Robotic OT FIN

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Nanavati NEURO OT

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Nanavati Hemodialysis Machine

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Nanavati Birth Centre OT

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Nanavati Birth Centre Recovery Room

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Nanavati BMT Corridor

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Nanavati Birth Centre Delivery Room

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Nanavati BMT Room

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Nanavati Birth Centre Recp

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Nursing Stationm

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OPD 2

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Paediatric Ward

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Twin Sharing Room

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About Nanavati Hospital

The iconic healthcare institution of Mumbai, Dr. Balabhai Nanavati Hospital, blessed by Mahatma Gandhi and inaugurated in 1950 by India’s first Prime Minister Jawaharlal Nehru, is now reintroduced as Nanavati Super Speciality Hospital.

Nanavati Super Speciality Hospital has been at the forefront of healthcare for 65 years. Today the 350 bed facility housing 55 speciality departments offers a plethora of services in practically every field of modern medicine and health care. Our well-equipped hospital rooms, state-of-the-art departments and technologically advanced systems are all backed by the expertise and reputation of over 350 consultants, 100 resident doctors, 475 nursing staff and 1500 employees.

The hospital’s state-of-the-art Imaging Centre, spanning over 10,000 sq. ft, houses 3 Tesla 32 channel wide bore Magnetic Resonance Imaging (MRI) scanner with MR guided Focused Ultrasound Surgery (MRgFUS) and High-Intensity-Focused-Ultrasound, 64 slice Positron Emission Tomography–Computed Tomography (PET CT) with cardiac capability. The Catheterization Lab at Nanavati Heart Centre which is the first of its kind in Mumbai, has a team of highly experienced and qualified faculty providing 24x7 Interventional Cardiac Services.

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+91-9152052058

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